Volume 5; Issue 3 Suppleme

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Arthritis Research & Therapy
Volume 5; Issue 3 Suppleme

Arthritis Research & Therapy

Volume 5; Issue 3 Suppleme

1

Fortieth Anniversary of APLAR

Journal:

Arthritis Research & Therapy

Year:

2003

Language:

english

File:

PDF, 554 KB

english, 2003

2

Assessing the burden of musculoskeletal conditions: a joint World Health Organization–Bone and Joint Decade project

N Khaltaev, B Pfleger, AD Woolf, C Mathers, K Akesson, JM Hazes…

Journal:

Arthritis Research & Therapy

Year:

2003

Language:

english

File:

PDF, 554 KB

english, 2003

3

Bioethics and research: scientific autonomy versus social responsibility. Should we lead or be led?

Journal:

Arthritis Research & Therapy

Year:

2003

Language:

english

File:

PDF, 554 KB

english, 2003

4

Celecoxib: a selective cyclooxygenase-2 inhibitor

Journal:

Arthritis Research & Therapy

Year:

2003

Language:

english

File:

PDF, 554 KB

english, 2003

5

From clinical pharmacology to clinical rheumatology: bench to bedside

Journal:

Arthritis Research & Therapy

Year:

2003

Language:

english

File:

PDF, 554 KB

english, 2003

6

Clinical feature of fibromyalgia syndrome in Japan and novel strategy in the treatment by bioproduct (Neurotropin)

H Nakamura, K Hoshi, T Kato, S Ozaki, M Nishioka, K Nishioka

Journal:

Arthritis Research & Therapy

Year:

2003

Language:

english

File:

PDF, 554 KB

english, 2003

7

Structural and functional changes in the brains of fibromyalgia subjects evaluated with single photon emission computed spectrometry and magnetic resonance imaging

K Pile, L Barnden, S Behin-Ain, L Yelland, D Danda, R Casse…

Journal:

Arthritis Research & Therapy

Year:

2003

Language:

english

File:

PDF, 554 KB

english, 2003

8

Exercise: medicine for knee cartilage?

L Dahlberg, E Roos, J Svensson, P Leander, CJ Tiderius

Journal:

Arthritis Research & Therapy

Year:

2003

Language:

english

File:

PDF, 554 KB

english, 2003

9

Pentosidine in serum and synovial fluid in patients with knee osteoarthritis and its potential role of prediction of osteoarthritis progression

K Pavelka, L Senolt, V Vilim, P Spacek, M Braun, S Forejtova

Journal:

Arthritis Research & Therapy

Year:

2003

Language:

english

File:

PDF, 554 KB

english, 2003

10

T cell–chondrocyte interaction in the pathogenesis of osteoarthritis

H Nakamura, T Kato, K Masuko-Hongo, M Tanaka, A Shibakawa, K Nishioka

Journal:

Arthritis Research & Therapy

Year:

2003

Language:

english

File:

PDF, 554 KB

english, 2003

11

Expression of focal adhesion kinase, Akt/PKB, Elk-1 and p90RSK in rheumatoid arthritis tissues but not at sites of cartilage invasion

CA Seemayer, S Kuchen, P Kuenzler, V Rihosková, J Schedel, M Neidhart…

Journal:

Arthritis Research & Therapy

Year:

2003

Language:

english

File:

PDF, 554 KB

english, 2003

12

Oxidative stress induces chondrocyte telomere instability and chondrocyte dysfunctions in osteoarthritis

K Yudoh, N van Trieu, H Matsuno, K Nishioka

Journal:

Arthritis Research & Therapy

Year:

2003

Language:

english

File:

PDF, 554 KB

english, 2003

13

Potentiality of mesenchymal stem cells withex vivogene therapy for osteochondral defect in arthritis

H Inoue, N Abe, J Lieberman

Journal:

Arthritis Research & Therapy

Year:

2003

Language:

english

File:

PDF, 554 KB

english, 2003

14

Hepatocyte growth factor in osteoarthritis: when bone and cartilage decide to have a chat

P Reboul, M Guévremont, J Martel-Pelletier, F Massicotte, P Ranger…

Journal:

Arthritis Research & Therapy

Year:

2003

Language:

english

File:

PDF, 554 KB

english, 2003

15

Apoptosis, loss of B-cell tolerance and lymphoid neogenesis in Sjögren's syndrome

Journal:

Arthritis Research & Therapy

Year:

2003

Language:

english

File:

PDF, 554 KB

english, 2003

16

Humoral, hormonal and genetic determinants of cholinergic dysfunction in Sjögren's syndrome

Journal:

Arthritis Research & Therapy

Year:

2003

Language:

english

File:

PDF, 554 KB

english, 2003

17

Immunological abnormality and regulation in patients with Sjögren's syndrome

Journal:

Arthritis Research & Therapy

Year:

2003

Language:

english

File:

PDF, 554 KB

english, 2003

18

Expanded circulating transitional B cells in a patient with systemic lupus erythematosus

R Ettinger, GP Sims, E Tackey, C Yarboro, G Illei, PE Lipsky

Journal:

Arthritis Research & Therapy

Year:

2003

Language:

english

File:

PDF, 554 KB

english, 2003

19

Identification of kinectin as a novel Behcet's disease-related autoantigen

Y Lu, P Ye, X Feng, S Chen, EM Tan, EKL Chan

Journal:

Arthritis Research & Therapy

Year:

2003

Language:

english

File:

PDF, 554 KB

english, 2003

20

Infliximab for severe ocular inflammation in patients with Behcet's disease

P Sfikakis, N Markomichelakis

Journal:

Arthritis Research & Therapy

Year:

2003

Language:

english

File:

PDF, 554 KB

english, 2003

21

C-reactive protein is an important immunoregulatory molecule that decreases systemic inflammatory response and ameliorates autoimmune disease

Journal:

Arthritis Research & Therapy

Year:

2003

Language:

english

File:

PDF, 554 KB

english, 2003

22

New aspects of the etiopathogenesis of systemic lupus erythematosus

US Gaipl, TD Beyer, RE Voll, S Franz, JR Kalden, M Herrmann

Journal:

Arthritis Research & Therapy

Year:

2003

Language:

english

File:

PDF, 554 KB

english, 2003

23

IgM and C1q function in the same pathway to promote the clearance of apoptotic cellsin vivo

K Elkon, R Kowaleski, V Montenegro, SJ Kim

Journal:

Arthritis Research & Therapy

Year:

2003

Language:

english

File:

PDF, 554 KB

english, 2003

24

Evidence for an IFN-inducible gene,Ifi202, in the susceptibility to systemic lupus

S Rozzo, D Choubey, T Vyse, S Izui, J Allard, G Peltz, B Kotzin

Journal:

Arthritis Research & Therapy

Year:

2003

Language:

english

File:

PDF, 554 KB

english, 2003

25

Enhanced proliferative response of CD4+T cells from patients with systemic lupus erythematosus by T-cell receptor stimulation

S Park, I Kang, H Kim, J Craft

Journal:

Arthritis Research & Therapy

Year:

2003

Language:

english

File:

PDF, 554 KB

english, 2003

26

The systemic lupus erythematosus VλJλ repertoire harbors characteristics of the natural antibody repertoire

J Lee, PE Lipsky

Journal:

Arthritis Research & Therapy

Year:

2003

Language:

english

File:

PDF, 554 KB

english, 2003

27

Antiphospholipid antibodies harness innate effectors, neutrophils and an alternative pathway of complement, to induce fetal damage

J Salmon, G Girardi, J Berman, J Thurman, VM Holers

Journal:

Arthritis Research & Therapy

Year:

2003

Language:

english

File:

PDF, 554 KB

english, 2003

28

The synovial cadherin (cadherin-11) mediates tissue formation and promotes invasion of fibroblast-like synoviocytes

H Kiener, J Higgins, X Valencia, M Brenner

Journal:

Arthritis Research & Therapy

Year:

2003

Language:

english

File:

PDF, 554 KB

english, 2003

29

The fibrinolytic pattern of rheumatoid synoviocytes is invasive like neoplastic cells

M Matucci-Cerinic, S Guiducci, A Del Rosso, M Cinelli, G Fibbi…

Journal:

Arthritis Research & Therapy

Year:

2003

Language:

english

File:

PDF, 554 KB

english, 2003

30

Triptolide, an active compound identified in a traditional Chinese herb, induces apoptosis of rheumatoid synovial fibroblasts

N Kusunoki, R Yamazaki, S Kawai

Journal:

Arthritis Research & Therapy

Year:

2003

Language:

english

File:

PDF, 554 KB

english, 2003

31

Laminin, but not lipopolysaccharide, IL-1 or tumor necrosis factor alpha, induces IL-16 gene activity in synovial fibroblasts

W Aicher, D Alexander, T Pap, S Gay

Journal:

Arthritis Research & Therapy

Year:

2003

Language:

english

File:

PDF, 554 KB

english, 2003

32

Synoviolin as a novel pathogenic factor for arthropathy

T Amano, S Yamasaki, N Yagishita, K Tsuchimochi, A Fukamizu…

Journal:

Arthritis Research & Therapy

Year:

2003

Language:

english

File:

PDF, 554 KB

english, 2003

33

The importance of Synoviolin in embryogenesis

N Yagishita, T Amano, S Yamasaki, T Tsuchimochi, K Nishioka…

Journal:

Arthritis Research & Therapy

Year:

2003

Language:

english

File:

PDF, 554 KB

english, 2003

34

Transcriptional regulation of Synoviolin is important for the proliferation of rhumatoid synovial cells

K Tsuchimochi, S Yamasaki, N Yagishita, T Amano, S Komiya, I Maruyama…

Journal:

Arthritis Research & Therapy

Year:

2003

Language:

english

File:

PDF, 554 KB

english, 2003

35

Pathogenetic roles of Synoviolin in synovial hyperplasia of rheumatoid arthritis

S Yamasaki, N Yagishita, T Amano, K Tsuchimochi, I Maruyama…

Journal:

Arthritis Research & Therapy

Year:

2003

Language:

english

File:

PDF, 554 KB

english, 2003

36

Floating anchorage-independent fibroblast-like cells mediate cartilage destruction independently from the hyperplastic synovial tissue

M Neidhart, CA Seemayer, BA Michel, RE Gay, S Gay

Journal:

Arthritis Research & Therapy

Year:

2003

Language:

english

File:

PDF, 554 KB

english, 2003

37

IL-15 and its role in rheumatoid arthritis

M Kurowska-Stolarska, O Distler, W Rudnicka, J Distler, RE Gay…

Journal:

Arthritis Research & Therapy

Year:

2003

Language:

english

File:

PDF, 554 KB

english, 2003

38

Enumeration and phenotypic characterization of synovial fluid multipotential mesenchymal progenitor cells in inflammatory and degenerative arthritis

D McGonagle, E Jones, A English, P Emery

Journal:

Arthritis Research & Therapy

Year:

2003

Language:

english

File:

PDF, 554 KB

english, 2003

39

Galectin-3 and galectin-3 binding protein in rheumatoid arthritis

S Ohshima, S Kuchen, C Seemayer, FT Liu, M Neidhart, RE Gay, S Gay

Journal:

Arthritis Research & Therapy

Year:

2003

Language:

english

File:

PDF, 554 KB

english, 2003

40

Soluble 4A11 antigen: a novel mediator of leukocyte-endothelial adhesion and monocyte recruitment in rheumatoid arthritis

A Koch, K Zhu, M Amin, Y Zha, M Kim, C Park, H Ruth, H Castro-Rueda…

Journal:

Arthritis Research & Therapy

Year:

2003

Language:

english

File:

PDF, 554 KB

english, 2003

41

The innate immune system as a therapeutic target in arthritis

M Corr, JY Choe, K Pekny

Journal:

Arthritis Research & Therapy

Year:

2003

Language:

english

File:

PDF, 554 KB

english, 2003

42

Gene transfer of p21Cip1exerts multiple molecular effects in the treatment of arthritis

H Kohsaka, Y Nonomura, K Nagasaka, N Miyasaka

Journal:

Arthritis Research & Therapy

Year:

2003

Language:

english

File:

PDF, 554 KB

english, 2003

43

Repeated B-cell depletion with rituximab in rheumatoid arthritis

J Edwards, M Leandro

Journal:

Arthritis Research & Therapy

Year:

2003

Language:

english

File:

PDF, 554 KB

english, 2003

44

Pathogenic roles of IL-6 and IL-6 blocking therapy on rheumatoid arthritis

K Yoshizaki, N Nishimoto, N Miyasaka, K Yamamoto, S Kawai, T Takeuchi…

Journal:

Arthritis Research & Therapy

Year:

2003

Language:

english

File:

PDF, 554 KB

english, 2003

45

Therapeutic inhibition of tumour necrosis factor alpha reduces oligoclonality in the selected T-cell receptor BV families in rheumatoid arthritis

M Pierer, U Wagner, S Kaltenhäuser, S Arnold, H Häntzschel

Journal:

Arthritis Research & Therapy

Year:

2003

Language:

english

File:

PDF, 554 KB

english, 2003

46

TNF-alpha blockade by nonviral gene therapy in collagen-induced arthritis

MC Boissier, C Bloquel, P Bigey, V Deleuze, D Scherman, N Bessis

Journal:

Arthritis Research & Therapy

Year:

2003

Language:

english

File:

PDF, 554 KB

english, 2003

47

Antirheumatic effects of humanized anti-Fas monoclonal antibody in human rheumatoid arthritis/SCID mouse chimera

H Matsuno, K Yudoh, K Nishioka

Journal:

Arthritis Research & Therapy

Year:

2003

Language:

english

File:

PDF, 554 KB

english, 2003

48

Regulatory T cells in experimental arthritis

R Bräuer, O Frey, PK Petrow, A Scheffold, A Radbruch

Journal:

Arthritis Research & Therapy

Year:

2003

Language:

english

File:

PDF, 554 KB

english, 2003

49

Essential role for migration inhibitory factor in IL-1 activation of mitogen-activated protein kinases

E Morand, D Lacey, Y Yang, M Leech, M Toh

Journal:

Arthritis Research & Therapy

Year:

2003

Language:

english

File:

PDF, 554 KB

english, 2003

50

Repair of local bone erosions by combined treatment with parathyroid hormone, osteoprotegerin and anti-tumor necrosis factor in tumor necrosis factor-transgenic mice

K Redlich, B Goertz, N Doerr, G Kollias, G Steiner, J Smolen…

Journal:

Arthritis Research & Therapy

Year:

2003

Language:

english

File:

PDF, 554 KB

english, 2003

51

CD44 regulates bone erosion and osteoclastogenesis in arthritis

G Schett, S Hayer, K Redlich, EF Wagner, G Kollias, G Steiner…

Journal:

Arthritis Research & Therapy

Year:

2003

Language:

english

File:

PDF, 554 KB

english, 2003

52

Changes in the synovial cell proteome induced by hypoxia

H El-Gabalawy, J Wilkins, K Dasuri, D Duggan

Journal:

Arthritis Research & Therapy

Year:

2003

Language:

english

File:

PDF, 554 KB

english, 2003

53

Skewed T-cell receptor BV14 and BV16 expression, and shared complementarity-determining region 3 sequence and common sequence motifs in synovial T cells of rheumatoid arthritis

W Sun, H Nie, N Li, Y Zang, D Zhang, G Feng, L Ni, R Xu, E Sercarz…

Journal:

Arthritis Research & Therapy

Year:

2003

Language:

english

File:

PDF, 554 KB

english, 2003

54

Significance of fatigue in patients with rheumatoid arthritis

G Singh, M Bennett, B Lingala, A Singh

Journal:

Arthritis Research & Therapy

Year:

2003

Language:

english

File:

PDF, 554 KB

english, 2003

55

The declining incidence of nonsteroidal anti-inflammatory drug gastropathy in rheumatoid arthritis patients: rates and reasons

J Fries, K Murtaugh, M Bennett, E Zatarain, B Lingala, B Bruce

Journal:

Arthritis Research & Therapy

Year:

2003

Language:

english

File:

PDF, 554 KB

english, 2003

56

T cell contact-mediated induction of tumor necrosis factor alpha in peripheral blood monocytes is inhibited by autologous serum in rheumatoid arthritis

U Wagner, M Rossol, S Kaltenhäuser, S Hauschild, H Häntzschel

Journal:

Arthritis Research & Therapy

Year:

2003

Language:

english

File:

PDF, 554 KB

english, 2003

57

Expression of IgVH mRNAs in plasma cells derived from rheumatoid arthritis synovium detected by single-cell RT-PCR

J Vencovský, Z Cimburek, J Niederlová, O Horvath, O Kryštùfková…

Journal:

Arthritis Research & Therapy

Year:

2003

Language:

english

File:

PDF, 554 KB

english, 2003

58

Autoantibodies in very early rheumatoid arthritis: diagnostic tools or pathogenic players?

G Steiner, V Nell, G Eberl, S Hayer, K Machold, E Hoefler, J Smolen

Journal:

Arthritis Research & Therapy

Year:

2003

Language:

english

File:

PDF, 554 KB

english, 2003

59

T-cell regulation in the pathogenesis of autoimmune diseases

H Schulze-Koops, PE Lipsky, JR Kalden, A Skapenko

Journal:

Arthritis Research & Therapy

Year:

2003

Language:

english

File:

PDF, 554 KB

english, 2003

60

Lymphoid neogenesis in chronic inflammation

C Pitzalis, A Manzo, S Paoletti, F Barone, R Caporali, CM Montecucco…

Journal:

Arthritis Research & Therapy

Year:

2003

Language:

english

File:

PDF, 554 KB

english, 2003

61

Evidence for functional variation of the death receptor 3 gene predisposing rheumatoid arthritis

S Shiozawa, K Komai, K Osaka, Y Miura, A Hashiramoto, K Shiozawa

Journal:

Arthritis Research & Therapy

Year:

2003

Language:

english

File:

PDF, 554 KB

english, 2003

62

Collagenous colitis and rheumatoid arthritis: is there a connection?

F Wollheim, A Domargård, J Bohr, C Tysk, T Skogh

Journal:

Arthritis Research & Therapy

Year:

2003

Language:

english

File:

PDF, 554 KB

english, 2003

63

Comparison of the nodule and synovial lesions of rheumatoid arthritis

J Highton, P Hessian

Journal:

Arthritis Research & Therapy

Year:

2003

Language:

english

File:

PDF, 554 KB

english, 2003

64

Serum activity of joint destruction proteinases in management of juvenile rheumatoid arthritis

E Yarygina, A Bogatyreva, S Zhanaeva, M Soboleva, T Korolenko

Journal:

Arthritis Research & Therapy

Year:

2003

Language:

english

File:

PDF, 554 KB

english, 2003

65

The impact of exogenous and endogenous nucleic acids on the development of joint inflammation

A Tarkowski, J Bjersing, M Bokarewa, LV Collins, GM Deng, S Hajizadeh…

Journal:

Arthritis Research & Therapy

Year:

2003

Language:

english

File:

PDF, 554 KB

english, 2003

66

Cas-L associates with human T-lymphotropic virus type I Tax and regulates its transactivation of NF-κB: possible role of Cas-L in pathophysiology of rheumatoid arthritis

S Iwata, A Souta-Kuribara, R Miyake-Nishijima, T Sasaki, H Kobayashi…

Journal:

Arthritis Research & Therapy

Year:

2003

Language:

english

File:

PDF, 554 KB

english, 2003

67

C5a controls the FcγR activation in inflammatory processes

Journal:

Arthritis Research & Therapy

Year:

2003

Language:

english

File:

PDF, 554 KB

english, 2003

68

Cell death and immune regulation:in vivoapplication of a novel agonistic monoclonal antibody for death receptor Fas

Journal:

Arthritis Research & Therapy

Year:

2003

Language:

english

File:

PDF, 554 KB

english, 2003

69

Antigen-specific suppression of inflammatory arthritis by dendritic cells

R Thomas, E Martin, B O'Sullivan

Journal:

Arthritis Research & Therapy

Year:

2003

Language:

english

File:

PDF, 554 KB

english, 2003

70

Immunosuppression and immunological tolerance induction: lessons from a transplant model

A Filatenkov, S Tullius, H Schmidt, A Selke, H Volk

Journal:

Arthritis Research & Therapy

Year:

2003

Language:

english

File:

PDF, 554 KB

english, 2003

71

Immunosuppressive effect of mesenchymal stem cells in collagen-induced arthritis

C Jorgensen, F Djaoud, F Apparilly, J Sany, D Noel

Journal:

Arthritis Research & Therapy

Year:

2003

Language:

english

File:

PDF, 554 KB

english, 2003

72

Induction of type II collagen-reactive IL-10-producing CD11b+dendritic cells in Payer's patch of orally tolerized animals

H Kim, M So-Youn, C Mi-La, L Jung-Eun, P Sung-Hwan, L Kang-Eun…

Journal:

Arthritis Research & Therapy

Year:

2003

Language:

english

File:

PDF, 554 KB

english, 2003

73

Dendritic cells present a tissue-specific autoantigen under steady state and autoimmune conditions in the draining lymph node

C Scheinecker, R McHugh, E Shevach, R Germain

Journal:

Arthritis Research & Therapy

Year:

2003

Language:

english

File:

PDF, 554 KB

english, 2003

74

Search for the precursor of ectopic follicular dendritic cells

C de Groot, C de Groot, F Muller, J Haringman, P Tak

Journal:

Arthritis Research & Therapy

Year:

2003

Language:

english

File:

PDF, 554 KB

english, 2003

75

Natural antibodies and antiphospholipid antibodies bind to injured tissues, activate complement and cause tissue damage

G Tsokos, S Fleming

Journal:

Arthritis Research & Therapy

Year:

2003

Language:

english

File:

PDF, 554 KB

english, 2003

76

Antileukoproteinase: modulation of neutrophil function and therapeutic effects in anticollagen II antibody-induced arthritis

H Burkhardt, B Sehnert, A Cavcic, B Boehm, K Nandakumar, R Holmdahl

Journal:

Arthritis Research & Therapy

Year:

2003

Language:

english

File:

PDF, 554 KB

english, 2003

77

Multiplex autoantibody profiling using 'synovial proteome' microarrays identifies citrulline-modified peptides as major targets of the autoimmune response in rheumatoid arthritis

W Hueber, BJ Lee, M Genovese, van W Venrooij, L Steinman, PJ Utz…

Journal:

Arthritis Research & Therapy

Year:

2003

Language:

english

File:

PDF, 554 KB

english, 2003

78

Impact of altered peptide derived from collagen II on T-cell activation and collagen-induced arthritis

Z Li, Q Zhou, Y Cheng, H Lu

Journal:

Arthritis Research & Therapy

Year:

2003

Language:

english

File:

PDF, 554 KB

english, 2003

79

Novel B-lymphocyte-deleting agents for the treatment of autoimmune diseases: induction of the mitochondrial pathway of apoptosis

G Silverman, CS Goodyear

Journal:

Arthritis Research & Therapy

Year:

2003

Language:

english

File:

PDF, 554 KB

english, 2003

80

Circulating anergic B cells in the periphery of active systemic lupus erythematosus patients: functional and phenotypic characterization

A Grammer, R Fischer, R Slota, N Longo, H Sohn, C Yarboro, G Illei…

Journal:

Arthritis Research & Therapy

Year:

2003

Language:

english

File:

PDF, 554 KB

english, 2003

81

The physiological immunosuppressive network and its putative role in the pathogenesis of autoimmunity: inhibition through signaling, cellular contact, anergy, apoptosis

H Lorenz, N Blank, M Kriegel, M Schiller, E Scherb, S Winkler…

Journal:

Arthritis Research & Therapy

Year:

2003

Language:

english

File:

PDF, 554 KB

english, 2003

82

Establishment of juvenile and tolerant immune systems in patients with autoimmune diseases treated with immunoablation and autologous stem cell therapy

A Radbruch, A Thiel, S Kimmig, T Alexander, E Gromnica-Ihle, F Hiepe…

Journal:

Arthritis Research & Therapy

Year:

2003

Language:

english

File:

PDF, 554 KB

english, 2003

83

IL-12 priming during initial antigen contact increases generation of effector and memory CD8 T cells by changing properties

J Chang, J-H Cho, S-Y Choi, S-J Ha, Y-C Sung

Journal:

Arthritis Research & Therapy

Year:

2003

Language:

english

File:

PDF, 554 KB

english, 2003

84

Human cartilage glycoprotein-39 directed T-cell responses in health and arthritic diseases

R Toes, J Van Bilsen, L Lard, A Miltenburg, F Breedveld, T Huizinga…

Journal:

Arthritis Research & Therapy

Year:

2003

Language:

english

File:

PDF, 554 KB

english, 2003

85

Role of β1 integrin and its signaling molecule, Cas-L, in pathophysiology and therapeutic interventigens of rheumatoid arthritis

Journal:

Arthritis Research & Therapy

Year:

2003

Language:

english

File:

PDF, 554 KB

english, 2003

86

Does sustained downregulation of the TCRzeta chain define the transition from antigen mode to inflammation mode in effector T lymphocytes?

A Cope, Z Zhang, J Clark, N Panesar, P Amjadi

Journal:

Arthritis Research & Therapy

Year:

2003

Language:

english

File:

PDF, 554 KB

english, 2003

87

Post-translational modification of type II collagen influences T-cell tolerance to self-type II collagen

H Yamada, R Holmdahl, T Shuto, Y Nakajima, J Shida, T Mawatari…

Journal:

Arthritis Research & Therapy

Year:

2003

Language:

english

File:

PDF, 554 KB

english, 2003

88

The Th2 cytokines IL-4 and IL-10 are internal controllers of human Th1-biased immunityin vivo

A Skapenko, GU Niedobitek, JR Kalden, PE Lipsky, H Schulze-Koops

Journal:

Arthritis Research & Therapy

Year:

2003

Language:

english

File:

PDF, 554 KB

english, 2003

89

Transplant-tolerance induction by CTLA-4Ig in liver-transplanted rats: a lesson for the treatment of autoimmune diseases?

U Fischer, S Boas-Knoop, U Neumann

Journal:

Arthritis Research & Therapy

Year:

2003

Language:

english

File:

PDF, 554 KB

english, 2003

90

Repertoire analysis of anergic B cells from patients with systemic lupus erythematosus

NS Longo, R Fischer, J Daruwalla, AC Grammer, PE Lipsky

Journal:

Arthritis Research & Therapy

Year:

2003

Language:

english

File:

PDF, 554 KB

english, 2003

91

New approach to chemical biology for drug discovery: construction of new affinity beads and their application

Journal:

Arthritis Research & Therapy

Year:

2003

Language:

english

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PDF, 554 KB

english, 2003

92

Gene hunting in primary osteoarthritis

Journal:

Arthritis Research & Therapy

Year:

2003

Language:

english

File:

PDF, 554 KB

english, 2003

93

The new application of chip technology to transcriptome and proteome analysis of rheumatoid disease

T Nakanishi, K Nishida, K Ohyama, M Takigawa, H Inoue

Journal:

Arthritis Research & Therapy

Year:

2003

Language:

english

File:

PDF, 554 KB

english, 2003

94

Modulation of the gene expression pattern in peripheral blood mononuclear cells by biologicals in rheumatoid arthritis

J Kekow, D Koczan, S Drynda, A Drynda, H Thiesen

Journal:

Arthritis Research & Therapy

Year:

2003

Language:

english

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english, 2003

95

Novel tools for molecular analysis in synovium

U Mueller-Ladner, E Neumann, I Tarner, J Grifka, O Distler, A Wunder…

Journal:

Arthritis Research & Therapy

Year:

2003

Language:

english

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english, 2003

96

Novel function of GATA-3, revealed by conditional deficient mice

IC Ho, SY Pai, ML Truitt

Journal:

Arthritis Research & Therapy

Year:

2003

Language:

english

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english, 2003

97

Sox9 represses gene expression via histone deacetylase activity

M Tsuda, S Takahashi, N Taniguchi, T Furumatsu, H Asahara

Journal:

Arthritis Research & Therapy

Year:

2003

Language:

english

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english, 2003

98

Transcriptional co-activator CBP/p300 regulates chondrocyte-specific gene expression via association with Sox9

S Takahashi, M Tsuda, Y Takahashi, H Asahara

Journal:

Arthritis Research & Therapy

Year:

2003

Language:

english

File:

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english, 2003

99

OLF1/EBF-associated zinc finger protein gene: a novel lupus susceptibility locus on chromosome 16q identified in a Chinese cohort

N Shen, XB Fong, SL Chen, Y Wang, BH Hahn, BP Tsao

Journal:

Arthritis Research & Therapy

Year:

2003

Language:

english

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english, 2003

100

Analysis of IL-10 gene variants in rheumatoid arthritis

T Huizinga, J Schonkeren, F Kureeman, van F Gaalen, R Westendorp…

Journal:

Arthritis Research & Therapy

Year:

2003

Language:

english

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english, 2003

101

Functional haplotypes in citrullinating enzyme peptidylarginine deiminase 4 are associated with rheumatoid arthritis

K Yamamoto, A Suzuki, X Chang, S Tokuhiro, T Sawada, Y Nakamura…

Journal:

Arthritis Research & Therapy

Year:

2003

Language:

english

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english, 2003

102

Molecular pain signalling in joints

H Sprott, H Shen, RE Gay, BA Michel, S Gay, A Aeschlimann

Journal:

Arthritis Research & Therapy

Year:

2003

Language:

english

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english, 2003

103

Unbalanced levels of bone resorption promoting factors in bone marrow from patients with rheumatoid arthritis in comparison to osteoarthritis

W Maslinski, J Jaworski, M Ziolkowska, J Kowalczewski, J Pazdur

Journal:

Arthritis Research & Therapy

Year:

2003

Language:

english

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english, 2003

104

Novel intracellular function of IL-1 receptor antagonist type 1 in endothelial cells

C Gabay, F Soussi, M Berti

Journal:

Arthritis Research & Therapy

Year:

2003

Language:

english

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english, 2003

105

Synergistic interactions of proinflammatory cytokines with oncostatin M: implications for joint destruction

T Cawston, H Wang, C Richards, A Rowan

Journal:

Arthritis Research & Therapy

Year:

2003

Language:

english

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english, 2003

106

IL-6 as a therapeutic target in systemic-onset juvenile idiopathic arthritis

S Yokota, T Miyamae, T Imagawa, M Mori

Journal:

Arthritis Research & Therapy

Year:

2003

Language:

english

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english, 2003

107

Role of lipoxins, antiflammins and serum amyloid A signaling via the common ALXR receptor in joint tissue inflammation

S Fiore, S Sodin-Semrl, G Antico, A Spagnolo, B Barbaro, J Varga…

Journal:

Arthritis Research & Therapy

Year:

2003

Language:

english

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english, 2003

108

Innate response cytokines in inflammatory synovitis: novel targets and strategies

I McInnes, BP Leung, JAG Gracie, D Xu, XQ Wei, J Brewer, FY Liew

Journal:

Arthritis Research & Therapy

Year:

2003

Language:

english

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english, 2003

109

Negative regulation of the hypoxia-inducible transcription factors by IPAS defines a novel anti-angiogenesis therapeutic strategy

Y Makino, L Poellinger, H Nakamura, C Morimoto, H Tanaka

Journal:

Arthritis Research & Therapy

Year:

2003

Language:

english

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english, 2003

110

IL-1 but not IL-18 induces osteoprotegerin and TRAIL in rheumatoid arthritis synovial fibroblasts

J Morel, R Audo, B Combe

Journal:

Arthritis Research & Therapy

Year:

2003

Language:

english

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english, 2003

111

Prostaglandin E2is an enhancer for IL-1β-induced expression of membrane-associated prostaglandin E synthase in rheumatoid synovial fibroblasts

F Kojima, H Naraba, S Kawai

Journal:

Arthritis Research & Therapy

Year:

2003

Language:

english

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english, 2003

112

15-deoxy-delta12,14-prostaglandin J2induces apoptosis in human articular chondrocytes

K Masuko-Hongo, Z-Z Shang, T Kato, H Nakamura, K Nishioka

Journal:

Arthritis Research & Therapy

Year:

2003

Language:

english

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english, 2003

113

Altered phosphorylation of Syp may be responsible for abnormal insulin-like growth factor-1 signaling in human osteoarthritic osteoblasts

D Lajeunesse, F Massicotte, I Aubry, J Martel-Pelletier, J Pelletier

Journal:

Arthritis Research & Therapy

Year:

2003

Language:

english

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english, 2003

114

Cartilage-derived morphogenetic protein-1 and cartilage-derived morphogenetic protein-2 are present in ligament fibroblasts and lead to chondrogenic differentiation

K Bobacz, L Erlacher, J Smolen, W Graninger

Journal:

Arthritis Research & Therapy

Year:

2003

Language:

english

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english, 2003

115

Tissue-engineered cartilage using thermoresponsive gelatin as anin situforming and moldable scaffold with chondrocytes:in vitroandin vivoperformances

S Ibusuki, T Matsuda, Y Iwamoto

Journal:

Arthritis Research & Therapy

Year:

2003

Language:

english

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english, 2003

116

CCAAT/enhancer-binding proteins mediate the repression of transcription of cartilage-derived retinoic acid-sensitive protein induced by IL-1β

K Okazaki, Y Iwamoto, L Sandell

Journal:

Arthritis Research & Therapy

Year:

2003

Language:

english

File:

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english, 2003

117

Cell biology and functional genomics of osteoarthritic chondrocytes

T Aigner, E Bartnik, R Zimmer

Journal:

Arthritis Research & Therapy

Year:

2003

Language:

english

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english, 2003

118

TNF-alpha induced chondrocyte apoptosis in NF-κB suppression is augmented by inhibition of p38 mitogen-activated protein kinase or phosphatidylinositol 3-kinase

Journal:

Arthritis Research & Therapy

Year:

2003

Language:

english

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english, 2003

119

The role of IL-4 in the control of mechanical stress-induced inflammatory mediators by rat chondrocytes

K Nishida, H Doi, A Shimizu, M Yorimitsu, M Takigawa, H Inoue

Journal:

Arthritis Research & Therapy

Year:

2003

Language:

english

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english, 2003

120

The effect of cyclooxygenase-2 selective inhibitors on the proliferation and apoptosis of human articular chondrocytes

YW Song, EB Lee, EM Park, JC Lee, YJ Lee

Journal:

Arthritis Research & Therapy

Year:

2003

Language:

english

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english, 2003

121

Evidence that rosiglitazone acts as an antidegradative agent on cartilage cellsin vitro

M Francois, L Tsagris, C Forest, P Richette, M Raymondjean, MT Corvol

Journal:

Arthritis Research & Therapy

Year:

2003

Language:

english

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english, 2003

122

Role of HC-gp39 in chondrogenesis: upregulation of SOX-9 expression by HC-gp39 in mouse chondrocytes

C Jacques, A Recklies, A Levy, A Labat, F Berenbaum

Journal:

Arthritis Research & Therapy

Year:

2003

Language:

english

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english, 2003

123

Overexpression and induction of heat shock protein 70 protect chondrocytes from cell deathin vitroandin vivo

L Grossin, C Cournil-Henrionnet, A Watrin-Pinzano, B Terlain…

Journal:

Arthritis Research & Therapy

Year:

2003

Language:

english

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english, 2003

124

Induction of heme oxygenase-1 inhibits IL-1b nitrite oxide production in articular chondrocytes

Journal:

Arthritis Research & Therapy

Year:

2003

Language:

english

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english, 2003

125

The JAK/STAT pathway but not the Erk1/2 pathway mediates IL-6/sIL-6R downregulation of type II collagen, aggrecan core and link protein transcription in articular chondrocytes

P Bogdanowicz, F Legendre, J Dudhia, J-P Pujol

Journal:

Arthritis Research & Therapy

Year:

2003

Language:

english

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english, 2003

126

Bone sparing effect of osteoprotegerin and anti-inflammatory cytokines in collagen-induced arthritis

M de Vernejoul, N Saidenberg, M Boissier, M Cohen-Solal

Journal:

Arthritis Research & Therapy

Year:

2003

Language:

english

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english, 2003

127

Bone cell differentiation and the role of Fos/AP-1 proteins

E Wagner, R Eferl, A Hoebertz, L Kenner, K Matsuo

Journal:

Arthritis Research & Therapy

Year:

2003

Language:

english

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english, 2003

128

TIMP-3 inhibits aggrecan breakdown in pig articular cartilage stimulated with IL-1

H Nagase, C Gendron, M Kashiwagi

Journal:

Arthritis Research & Therapy

Year:

2003

Language:

english

File:

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english, 2003

129

Regulation of collagenase-3 (MMP-13) gene and protein expression in human cartilage: when simple things get complicated

J Martel-Pelletier, G Tardif, JP Pelletier

Journal:

Arthritis Research & Therapy

Year:

2003

Language:

english

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english, 2003

130

New strategies for thein vivoregulation of metalloprotease gene expression in osteoarthritis chondrocytes by inflammatory mediators

JP Pelletier, C Boileau, D Schrier, C Flory, J Brunet, F Mineau…

Journal:

Arthritis Research & Therapy

Year:

2003

Language:

english

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english, 2003

131

Cell biology of synovial inflammation and secondary osteoporosis in rheumatoid arthritis

Y Tanaka, Y Okada, S Nakayamada, K Nakano, K Fujii, K Saito

Journal:

Arthritis Research & Therapy

Year:

2003

Language:

english

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english, 2003

132

Immunologic reactants in the pathogenesis of atherosclerosis in rheumatic diseases

B Cronstein, A Reiss

Journal:

Arthritis Research & Therapy

Year:

2003

Language:

english

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english, 2003

133

Mechanisms of resistance against Fas-induced apoptosis in rheumatoid arthritis synovial fibroblasts

T Pap, A Baier, I Meinecke, A Drynda, R Gay, W Neumann, S Gay

Journal:

Arthritis Research & Therapy

Year:

2003

Language:

english

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english, 2003

134

Candidate targets for antibody therapy of rheumatoid arthritis: CD64 and IL-15

J van de Winkel

Journal:

Arthritis Research & Therapy

Year:

2003

Language:

english

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english, 2003

135

TNF dependency of IL-17-induced joint pathology can be circumvented by Toll-like receptor-2 signaling

W Van den Berg, M Koenders, P van Lent, L Joosten, E Lubberts

Journal:

Arthritis Research & Therapy

Year:

2003

Language:

english

File:

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english, 2003

136

Activation of synovial fibroblasts via Toll-like receptor signaling

D Kyburz, M Pierer, J Rethage, R Seibl, RE Gay, DA Carson, S Gay

Journal:

Arthritis Research & Therapy

Year:

2003

Language:

english

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english, 2003

137

Complement, its role in innate immunity and autoimmunity

Journal:

Arthritis Research & Therapy

Year:

2003

Language:

english

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english, 2003

138

Variability of pro-apoptotic properties of cyclooxygenase-2 inhibitors in rheumatoid synovial fibroblasts and cancer cell lines

S Kawai, N Kusunoki, R Yamazaki

Journal:

Arthritis Research & Therapy

Year:

2003

Language:

english

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english, 2003

139

IL-21R mRNA is overexpressed in systemic sclerosis and contributes to the epidermal/dermal cross-talk

O Distler, J Distler, A Hirth, U Müller-Ladner, M Matucci-Cerinic…

Journal:

Arthritis Research & Therapy

Year:

2003

Language:

english

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english, 2003

140

The role of mPGES-1 for prostaglandin E2production in primary human synovial cells

L Crofford, M Qian, A Sampey, V Lath, S Guo, M Peters-Golden…

Journal:

Arthritis Research & Therapy

Year:

2003

Language:

english

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english, 2003

141

PPARγ ligands inhibit catabolic and inflammatory responses in articular joint cells

H Fahmi, J-P Pelletier, F Mineau, J Martel-Pelletier

Journal:

Arthritis Research & Therapy

Year:

2003

Language:

english

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english, 2003

142

IFN-β for the treatment of rheumatoid arthritis?

P Tak, van J Holten, K Reedquist, P Sattonet-Roche, T Smeets…

Journal:

Arthritis Research & Therapy

Year:

2003

Language:

english

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english, 2003

143

Human adipose tissue is an important novel source of IL-1Ra: a new connection between immuno-inflammatory diseases and lipid metabolism

J Dayer, C Meier

Journal:

Arthritis Research & Therapy

Year:

2003

Language:

english

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english, 2003

144

Effect of the combination of the proinflammatory cytokines IL-1, tumor necrosis factor-α and IL-17

P Miossec, C Granet, G Chevrel

Journal:

Arthritis Research & Therapy

Year:

2003

Language:

english

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english, 2003

145

Chemokines in rheumatoid arthritis: novel, potential therapeutic targets of the CCR2 chemokine receptor signaling pathway

K Matsushima, Y Terashima, M Haino

Journal:

Arthritis Research & Therapy

Year:

2003

Language:

english

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english, 2003

146

Failure of receptor revision in the autoreactive B cells in patients with systemic lupus erythematosus

H Yoshikawa, H Nagafuchi, M Kurokawa, T Sakane, N Suzuki

Journal:

Arthritis Research & Therapy

Year:

2003

Language:

english

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english, 2003

147

A Phase I trial of B-cell depletion with anti-CD20 monoclonal antibody (rituximab) in the treatment of systemic lupus erythematosus

R Eisenberg, D Albert, J Stansberry, D Tsai, S Kolasinski, S Khan

Journal:

Arthritis Research & Therapy

Year:

2003

Language:

english

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english, 2003

148

Antiphospholipid antibodies and thrombosis: pathogenesis of antiphospholipid syndrome

Journal:

Arthritis Research & Therapy

Year:

2003

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english

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english, 2003

149

Analysis of B-cell subpopulations in systemic lupus erythematosus

T Dorner, A Jacobi, M Odendahl, GR Burmester, A Radbruch, G Valet…

Journal:

Arthritis Research & Therapy

Year:

2003

Language:

english

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english, 2003

150

Origins of systemic lupus erythematosus: genes, environment, and host immune response

JB Harley, JA Kelly, JA James

Journal:

Arthritis Research & Therapy

Year:

2003

Language:

english

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english, 2003

151

Cyclin kinase inhibitors and interferons in lupus

A Theofilopoulos

Journal:

Arthritis Research & Therapy

Year:

2003

Language:

english

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english, 2003

152

Implication of Synoviolin in pathogenesis of arthropathy

Journal:

Arthritis Research & Therapy

Year:

2003

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english

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english, 2003

153

Role of bone morphogenetic protein signals during skeletal development

N Tsumaki, M Horiki, T Kimura, H Yoshikawa

Journal:

Arthritis Research & Therapy

Year:

2003

Language:

english

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english, 2003

154

Cellular therapies in musculoskeletal diseases: synovial-derived mesenchymal stem cells

Journal:

Arthritis Research & Therapy

Year:

2003

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english

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english, 2003

155

Transcription mechanism of chondrogenesis

Journal:

Arthritis Research & Therapy

Year:

2003

Language:

english

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english, 2003

156

Regulation of RANKL signaling in arthritic bone destruction

Journal:

Arthritis Research & Therapy

Year:

2003

Language:

english

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english, 2003

157

Role of BH3-only protein Bim in autoimmune and degenerative diseases

P Bouillet, S Cory, J Adams, A Strasser

Journal:

Arthritis Research & Therapy

Year:

2003

Language:

english

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english, 2003

158

Regulation of synovial cell function by adenovirus vector-mediated gene transduction

S Tanaka, H Seto, H Oda, K Nakamura

Journal:

Arthritis Research & Therapy

Year:

2003

Language:

english

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english, 2003

159

Proteomic surveillance of autoimmunity in osteoarthritis

T Kato, Y Xiang, T Sekine, H Nakamura, S Imajoh-Ohmi, H Fukuda…

Journal:

Arthritis Research & Therapy

Year:

2003

Language:

english

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english, 2003

160

The actions of BAFF in B-lymphocyte maturation and its effects on the development of autoimmune disease

Journal:

Arthritis Research & Therapy

Year:

2003

Language:

english

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english, 2003

161

Toll-like receptor family: receptors essential for microbial recognition and immune responses

S Akira, M Yamamoto, K Takeda

Journal:

Arthritis Research & Therapy

Year:

2003

Language:

english

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english, 2003

162

Characterization of signaling complexes at the T-cell antigen receptor

Journal:

Arthritis Research & Therapy

Year:

2003

Language:

english

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english, 2003

163

GRAIL: a gene related to anergy in lymphocytes

G Fathman, L Soares, N Anandasabapathy, C Seroogy

Journal:

Arthritis Research & Therapy

Year:

2003

Language:

english

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english, 2003

164

Cytokine production by dendritic cells genetically engineered to express IL-4: induction of Th2 responses and differential regulation of IL-12 and IL-23 synthesis

D Fox, Y Morita, R Gupta, K Seidl, K McDonagh

Journal:

Arthritis Research & Therapy

Year:

2003

Language:

english

File:

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english, 2003

165

The role of IL-17 in the development of arthritis in mouse models

Y Iwakura, S Nakae, R Horai, S Saijo

Journal:

Arthritis Research & Therapy

Year:

2003

Language:

english

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english, 2003

166

SKG mice, a new genetic model of rheumatoid arthritis

S Sakaguchi, T Takahashi, H Hata, T Nomura, N Sakaguchi

Journal:

Arthritis Research & Therapy

Year:

2003

Language:

english

File:

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english, 2003

167

Albumin-based drug delivery as novel therapeutic approach for rheumatoid arthritis

A Wunder, U Muller-Ladner, E Stelzer, E Neumann, H Sinn, S Gay…

Journal:

Arthritis Research & Therapy

Year:

2003

Language:

english

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english, 2003

168

Synovial mast cells require C5a receptor (CD88) for arthritis induction

D Lee, M Brenner, C Gerard, C Benoist, D Mathis, G Watts

Journal:

Arthritis Research & Therapy

Year:

2003

Language:

english

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english, 2003

169

The use of animal models to find and understand arthritis genes

Journal:

Arthritis Research & Therapy

Year:

2003

Language:

english

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english, 2003

170

Premise: traditional disease-modifying antirheumatic drugs are less effective and safe than targeted therapy with biologic response modifiers in rheumatoid arthritis

Journal:

Arthritis Research & Therapy

Year:

2003

Language:

english

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english, 2003

171

Delineating biologic pathways involved in skeletal growth and homeostasis through the study of rare Mendelian diseases that affect bones and joints

Journal:

Arthritis Research & Therapy

Year:

2003

Language:

english

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english, 2003

172

Interferons and IRF/Stat transcription factors in the regulation of immunity, oncogenesis and bone remodeling

T Taniguchi, A Takaoka, H Takayanagi, K Honda

Journal:

Arthritis Research & Therapy

Year:

2003

Language:

english

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english, 2003

173

Fifty years' experience in resarch for pathogenesis of rheumatoid arthritis.

Journal:

Arthritis Research & Therapy

Year:

2003

Language:

english

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english, 2003

174

Paracrine pathways of cartilage destruction in osteoarthritis

S Abramson, M Attur, M Dave, M Leung, J Patel, P Gomez, A Amin

Journal:

Arthritis Research & Therapy

Year:

2003

Language:

english

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english, 2003

175

DNA degradation during apoptotic cell death

Journal:

Arthritis Research & Therapy

Year:

2003

Language:

english

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english, 2003

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